mgr inż. Bożena Tyszczuk, mgr Anna Kuranc, dr. n. biol. Renata Dębowska, dr n. farm. Katarzyna Rogiewicz, dr n. farm. Irena Erisa
Key words: acne comedonal, acne comedonal-papular, azeloglycine, shikimic acid, niacinamideery, patient comfort, aesthetic effects
Abstract
Introduction: Acne comedonal affects people with all skin types. Its first symptom is Microcomedones. In adults, there is a comedonal-papular or papulo–pustular type.
The aim of the study was to evaluate the safety and effectiveness of an emulsion containing 1.5% azeloglycine, 1.5% shikimic acid and 1% niacinamide in patients with adult acne.
Material and methods: The tests of the emulsions in laboratory conditions included the assessment of irritating, antibacterial and antioxidant activity. The efficacy and safety of the preparation was assessed (instrumental and subjective studies) in persons with adult acne.
Results: The product did not show any irritating properties (both in in vitro and in vivo tests) and was not found to be sensitizing. The tested emulsion has anti-radical and antibacterial activity. The results of the studies in patients confirmed the high effectiveness of anti-acne action and seborrhea regulating effect as well as the effect of smoothing the skin and reducing the visibility of enlarged pores.
Conclusions: The preparation containing azeloglycine, shikimic acid and niacinamide effectively reduced acne lesions, comedones, smoothed the skin structure, reduced the visibility of enlarged pores and eliminated excessive skin shine. The product can be recommended to persons with adults acne and people prone to seborrhea.
