Esketamine as an antidepressant
prof. dr hab. Andrzej Pilc Key words: ketamine, S-ketamine, antidepressant effect, NMDA receptor Abstract Esketamine is the (S)(+) isomer of ketamine, both of them belong to the group of psychedelics. Ketamine was first used as a general anesthetic. Later, its mechanism of action was discovered, which is the blockade of NMDA receptors for glutamate. Blocking …